The 50 Best Places to Travel in 2022

From far-flung destinations to hometown favorites, 2022 is the year to get back out there and turn your dream trips into reality.

Planning new adventures as a new year approaches is always a thrill, but finding the best places to visit in 2022 is unique. After two years of border closures, cruise cancellations, and travel restrictions galore, 2022 is the year we hope to get back out there, uninhibited (albeit vaccinated and COVID tested), return to our favorite destinations, and cross new ones off our lists.

Though the hospitality industry was hit hard by the pandemic, many properties used the forced downtime to renovate rooms, add new amenities, and expand outdoor spaces to offer even more once guests return. 2022 is when many travelers will venture further from home, and even overseas, for the first time since the start of the pandemic, finally reaping the benefits of these valiant efforts.

Although COVID variants remain, regulations are still evolving, and precautions must still be taken, many of the destinations we chose for 2022 offer what we believe travelers are looking for in a post-pandemic world, from hotels with private accommodations to destinations teeming with fresh-air activities. Others, like Las Vegas, are for those who are ready and raring to make up for all the social time they missed — with a few splashy headliners, including Adele and the Raiders, thrown in for good measure.

As cruising makes its comeback, we included unforgettable places to see by water, from Antarctica to the Nile, and as hard-hit destinations like Italy and Asia recover, we found the buzziest reasons to return. Of course we didn't forget about all the stateside gems we got to know while domestic travel was surging, from Alaska and California to Florida and Michigan.

Our 2022 list, organized alphabetically, doesn't hold back, with aspirational trips as far away as India, Mozambique, Qatar, and even space — but we're also including hometown favorites, like Walt Disney World and its new Star Wars hotel; the wellness retreats of beautiful Sedona; and the simple pleasures of small-town, farm-to-table living in Franklin, Tennessee. Because no matter what type of trip you've been dreaming of, we want to help you turn 2022 into the year you get back out there and make it a reality.

— Edited by Nina Ruggiero and Scott Bay

1. Abruzzo, Italy

Lake Barrea, Italy - embedded in the wonderful Abruzzo, Lazio and Molise National Park,
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Stretching from the heart of the Apennines to the Adriatic Sea on the peninsula's southeastern side, Abruzzo, Italy has long been one of the country's most overlooked destinations despite its unspoiled villages, picturesque Trabocchi Coast, and stunning natural escapes. Over the past few years, however, it has gone from a sleepy underdog to an ambitious harbinger of slow travel, sustainable gastronomy, and conscious hospitality. Villa Corallo, a 19th-century mansion near Civitella del Tronto was transformed into a five-star hotel in 2019. Dimore Montane, an eco-lodge opened in 2020 in Majella National Park, marries glamping with environmentally-friendly facilities with a zero waste policy. Meanwhile, restaurants like Bottega Culinaria in San Vito Chietino and Materia Prima in Castel di Sangro are redefining the region as one of Italy's most exciting food hotspots for their innovative and sustainable takes on local produce and traditional dishes (in case Niko Romito's three-Michelin-starred Reale wasn't enough). And completing construction this Spring is Via Verde dei Trabocchi: a cycling and pedestrian path along the Adriatic sea that's being built on a disused railway route. — Marianna Cerini

2. Alaska

Aerial view at sunset of a vast wintery landscape of pine trees covered in snow off Dalton Highway in Alaska
Courtesy of Alaska Scenic Train

With many international borders closed over the last two years, many eager U.S. travelers' eyes turned to Alaska. The vast state, famous for its towering, snow-capped peaks, pristine wilderness, massive national parks, and colorful locals, made for a dynamic destination with no passport required. But as borders reopen, interest in the 49th state is showing no signs of slowing down. Alaska's tourism board said early forecasts are projecting that more than 1.57 million cruise ship passengers could visit southeast Alaska in summer 2022. That's an 18% jump from 2019, the previous record year. Many perennial favorite cruise lines, like Holland America, will be returning to full strength after a non-existent 2020 and abbreviated 2021. Others, like Windstar Cruises, UnCruise, and Hurtigruten are rolling out fresh itineraries or are launching new ships. On dry land, Alaska is set to see myriad new offerings and events. In Juneau, the Sealaska Heritage Institute will open their Arts Campus (where visitors will be able to learn about Alaska Native art and culture) and will host Celebration, one of the largest gatherings of Indigenous peoples. In Anchorage, Fur Rendezvous, Alaska's oldest and largest winter festival, will be back from Feb. 25 to March 6 (which also happens to be peak aurora season). The event hosts activities like the Running of the Reindeer and the Outhouse Races, before culminating with the 50th running of the iconic Iditarod Trail Sled Dog Race. — Bailey Berg

3. Anguilla

Long Bay Village, Anguilla
Shawn Walters/EyeEm/Getty Images

This easy-going Caribbean gem is simpler than ever to get to with American Airlines launching the first-ever nonstop, direct flight from Miami on Dec. 11. Private charter flights by Tradewind Aviation have also resumed service to the island. And the just-opened Aurora Anguilla Resort & Golf Club has a fleet of jets to ferry guests from key U.S. cities. The sprawling luxury resort will include a few restaurants overseen by chef Abram Bissell, formerly of Eleven Madison Park, The NoMad, and The Modern. Quintessence, a boutique luxury resort with perks like butler service and a 4:1 staff-to-guest ratio, is opening a more affordable annex of suites called Quinn that will debut in 2022 (along with a Champagne cellar tasting room and Art Bar). New Restaurant Uchu at Belmond Cap Juluca is taking inspiration from Belmond's collection of properties in Peru. Named after the Quechuan word for spice, the menu will feature contemporary Peruvian cuisine inspired by three of the country's regions: the coast, the jungle, and the highlands. — Scott Bay

4. Antarctica

Penguins on a cliff in Danco Island, Errera Channel, Graham Land, Antarctic Peninsula, Antarctica
Page Chichester/Getty Images

The pandemic shutdown created a compelling reason to visit Antarctica in 2022: See how the whales, seals, and penguins react after nearly two years without seeing humans. New polar-class expedition ships and new ways to get to the White Continent are reasons to pack your boots too. Viking Expeditions will be in Antarctica for the first time in 2022 with new, twin 378-passenger expedition ships. Ponant's new 270-passenger Le Commandant Charcot introduces eco-friendlier sailing, as the first hybrid-electric ship fueled by liquified natural gas (rather than heavy fuel). Quark Expeditions' long-awaited 199-passenger Ultramarine delivers exciting heli-hiking adventures via two eight-seat twin-engine helicopters. Hit a craps table in between icy exploration on the luxurious new all-suite 200-passenger Crystal Endeavor. Silversea Cruises' posh, 144-passenger, all-suite Silver Explorer returns with a debut travel option: Skip the notorious (for rough water) Drake Passage and catch a private flight directly from Chile to Antarctica to board the ship. — Fran Golden

5. Bahamas

View of palm tree lined beach from clear blue water in Nassau, Bahamas
Manfred Muenzl/EyeEm/Getty Images

American travelers have long loved the Bahamas for its crystal-clear waters, sandy beaches, and sunshine just about 50 miles off the coast of Florida, but there are even more reasons to visit the island nation in 2022. Baha Mar on the Island of New Providence has a brand new water park equipped with everything from a lazy river to a surf simulator, and day passes are available for purchase to those who aren't resort guests. For more rest and relaxation, journey to the outer islands of the Bahamas. While charter flights will get you exactly where you need to go, Crystal Cruises is offering a Bahamas-centric cruise that brings guests to some of the quieter and more remote islands. On its mid-July cruise, guests will embark and disembark from Nassau and then be whisked away via "6-star" service to the islands of Bimini, Great Exuma, San Salvador, and Long Island. Beyond the beach, don't forget to indulge in some local food and culture. The Island archipelago is famous for its conch, stew fish, and rock lobster. From late April through early May, Carnival is celebrated in Nassau and back after a pandemic hiatus. Keep an eye out for the famous sound and dance of the junkanoo. — Jamie Aranoff

6. Barbados

Local lady walking down the main street of the fishing village of Oistins, on the south coast of the Caribbean island of Barbados
Philip Willcocks/Getty Images

Whether you want a relaxing all-inclusive stay or a vibrant vacation filled with dining and nightlife, Barbados has you covered. Nowhere is that more evident than the pedestrian-friendly South Coast, which is teeming with new resorts and restaurants. The O2 Beach Club & Spa is an all-inclusive resort set on the white sands of Dover Beach, with three pools, six dining options, seven bars, and the Acqua spa, featuring the only hammam treatment room on the island. It joins other luxurious South Coast hotels, including Sandals and Sea Breeze Beach House. If you can pull yourself away from the resort pools, head along the coast to Worthing Square Food Garden, an outdoor food hall with 20 vendors serving dishes from around the Caribbean. Or stroll down the mile-long boardwalk for easy access to ocean-front food and drinks at local favorites like Champers, Salt Café, Tiki Bar, and Chill Café & Bar. — Kevin Gray

7. Belize

Caracol ruins in Belize

Taylor McIntyre/Travel + Leisure

A favorite of adventure travelers for its rainforests and divers who explore the Great Blue Hole and expansive barrier reef, Belize offers an abundance of casual spots and a handful of luxe resorts. The latest arrival is Alaia Belize, an Autograph Collection Hotel, in San Pedro on Ambergris Caye, opened mid-2021 with plans to add to its already extensive guest room, suite, and oceanfront villa accommodations. Major airlines are also recognizing the destination's potential with nonstop flights and convenient connections from most U.S. cities. In addition to United and Delta's nonstop flights from Houston and Atlanta, respectively, Alaska Airlines added nonstop service from Los Angeles and Seattle to Belize City in November, and Frontier Airlines will start weekly nonstop flights from Denver and Orlando. — Patricia Doherty

8. Budapest, Hungary

Typical Yellow Tram on the Danube Riverside near Hungarian Parliament building in Budapest, Hungary
Alan Tow/Getty Images

Very few places in the world capture both old-world charm and elegant modernity like Hungary's capital city, and Budapest's latest 130-room luxury hotel, Matild Palace, is a shining example. The neo-baroque palace-turned-hotel, which opened last summer in the city's District V, is a UNESCO-protected site that once housed the city's royalty. The hotel is now home to Wolfgang Punk's famed restaurant, Spago, the first of its kind in central Europe. It also hosts the Duchess bar — a rooftop "liquor library" that mixes craft cocktails using local wines and pálinka, Hungarian fruit brandy, which can be enjoyed alongside panoramic views of the Danube river. Surrounded by 22 wine regions, Budapest is a city for oenophiles. Enjoy a glass of Kékfrankos or Kadarka in the Castle District's newly opened wine bar, Takler Borbár Buda, founded by one of the country's renowned winemaking families. Don't leave the city without visiting Marlou, a biodynamic wine bar near the Hungarian State Opera, and Portobello, an unassuming coffee and natural wine bar around the corner from Matild Palace. — Stephanie Andrews

9. Burgundy, France

Hot air balloon and grapevines near Beaune in Burgundy
Tim Starke/Getty Images

The region of Burgundy is known for — you guessed it — its Burgundy wine, but French wine isn't the only reason Burgundy is a must-visit in 2022. In the spring, the region's capital city of Dijon will welcome the Cité Internationale de la Gastronomie et du Vin (International City of Gastronomy and Wine), an expansive complex with a cooking school, a new hotel, a handful of restaurants, and a wine cellar with over 250 by-the-glass offerings. The new project is perfectly situated at the starting point of Burgundy's famed wine route — Route des Grands Crus — which runs from Dijon to Santenay and produces some of the country's most well-regarded wines, including pinot noir, chardonnay, and sauvignon blanc. — Evie Carrick

10. British Virgin Islands

Aerial view at golden hour of Moskito Island
Courtesy of Moskito Island

Within the Caribbean, the 60 islands that comprise the British Virgin Islands have long held the reputation of luxury draped in relaxation. And now it's doubling down on that brand of island spirit with Richard Branson's second private island, the 125-acre Moskito Island that opened in October and sits right across from his first BVI paradise, Necker Island (which received a serious upgrade when it reopened last year after a two-year closure). The new destination will eventually have 10 private estates that can be rented through Virgin Limited Edition, but among the ones already available are Point Estate, starting at $17,500 a night, and Oasis Estate for $19,000. But Moskito isn't the only shiny new reason to visit BVI. Proving the area's resilience following the devastation after Hurricanes Irma and Maria, Saba Rock, the private island long known for its diving, went through a complete reconstruction before reopening in October; the Bitter End Yacht Club reopened in December with BVI's first over-the-water bungalows; and Oil Nut Bay will expand in early 2022 with new villas, a watersports center, and spa. Also on tap for 2022, the solar-powered White Bay Villas and new hilltop suites at Long Bay Beach Resort. And with the Spring Regatta and Sailing Festival returning in the spring of 2022 after being canceled for two years, BVI is proving it's truly back and stronger than ever. — Rachel Chang

11. Costa Smeralda, Sardinia

View from above, stunning aerial view of a green coastline with some beautiful beaches and a yacht sailing on a turquoise water. Liscia Ruja, Costa Smeralda, Sardinia, Italy.
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You're likely to glimpse Europe's pro athlete and yachting crowds at Marriott's four hotels on the Costa Smeralda, the glitzy Italian destination known for its Caribbean-like beaches and luxury resorts. Its glamorous Hotel Cala di Volpe has gradually been unveiling room renovations alongside new dining options, including its Harrods Suite, with a roof terrace and sea-facing plunge pool, and BeefBar's first Italian outpost. The entire area is one big "Billionaire Experience," but Formula One and entertainment mogul Flavio Briatore snagged the term for his new dining and nightlife venue in designer shopping destination Porto Cervo. For more of a low-key, family-friendly escape, the Baglioni Resort Sardinia opened an hour south in San Teodoro in June, overlooking the stunning Tavolara Marine Reserve. — Nina Ruggiero

12. Crete, Greece

Beautiful evening in Hersonissos bay, Crete, Greece
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The Greek Islands have long been a perennial favorite vacation destination for discerning travelers, and Crete, the largest of the 227 islands in the archipelago, deserves a spot atop your must-see list. Yes, it's a place where you can find the white-washed buildings and blue roofs you've lusted after on Instagram for years, and a spot where you can dive into the cerulean blue waters of the Mediterranean at every turn. And of course you can dig deep into both history and mythology as humans have lived on the island since the 7th millennium B.C., not to mention the fact that Crete is the birthplace of Zeus. It's little surprise then, with all this beauty and history, that Crete continues to harbor a rich creative community, mostly centered in the neighborhood of Chania. There, visitors can peruse works in museums like the Mediterranean Architecture Center, or seek out unique pieces in galleries like the Municipal Art Gallery or the Redd Gallery. To visit Crete, hop aboard a sailing with Silversea, which takes guests to Crete and several other stellar islands, or book a stay at the Blue Palace Elounda, a Luxury Collection Resort, named one of the Top 10 Greece Resort Hotels in Travel + Leisure's World's Best Awards, 2021. — Stacey Leasca

13. Walt Disney World

a starship cabin at Star Wars: Galactic Starcruiser at Walt Disney World Resort in Lake Buena Vista, Fla.,
David Roark/Courtesy of Disney

The "World's Most Magical Celebration" — Walt Disney World's 18-month-long 50th anniversary event that kicked off on Oct. 1 — continues through 2022 with enchanting touches and highly anticipated ride and hotel openings. Star Wars: Galactic Starcruiser will begin offering its immersive, two-night adventures in a galaxy far, far away on March 1. The interactive, choose-your-own-adventure experience will have guests wielding lightsabers, sleeping on the ship, brushing shoulders with Star Wars characters, eating intergalactic cuisine, and maybe even going on a secret mission, making this a truly unique experience that you can't find anywhere else in the world. Other 2022 openings include the Guardians of the Galaxy: Cosmic Rewind indoor coaster at Epcot, slated for summer. — Elizabeth Rhodes

14. Doha, Qatar

The marina waterfront walkway at the Pearl in Doha, Qatar, with shops and restaurants
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As we ask ourselves what cities of the future should look like, we naturally look around for examples. Places like Shanghai, Tokyo, and New York City seem to fit the description on paper, but I'd argue that no city better encapsulates that definition than Doha, the capital of Qatar. There is so much to discover — from East-West/West-East, a series of four steel monoliths created by sculptor Richard Serra to the Museum of Islamic Art, the massive 560,000-square-foot gallery. Eat at Syrian comfort food spot Damasca One, Em Sherif a rooftop spot that serves up authentic regional dishes, and the lively corner restaurant Nourlaya Contemporary for Sri Lankan cuisine. Stay at the Mandarin Oriental Doha or Banyan Tree Doha. (Read Robinson's full dispatch on Doha in the July 2021 edition of Travel + Leisure) — Whitney Robinson

15. Edinburgh, Scotland

Skyline, Dean Village, Edinburgh, Lothian, Scotland
Joe Daniel Price/Getty Images

The Auld Reekie is buzzing with new energy. The highly anticipated Hotel W, designed by Jestico and Whiles in conjunction with Allan Murray Architects, is opening next winter. And several other hotels have recently opened in and around the city — Marine North Berwick, the Market Street hotel, Rusacks St. Andrews, and ship-turned-luxury-hotel Fingal. Gleneagles Townhouse, a first-ever city outpost from the famed Gleneagles estate, is opening in the spring. St James Quarter, a developing area of the city, and where Hotel W is being built, is opening next year with 85 shops, 30 restaurants, and a cinema. New in whisky is the September christening of Johnnie Walker Princes Street. And promising to shake up the scotch scene in the capital city is Leith Distillery, opening in the summer. — Scott Bay

16. Finger Lakes, New York

Taughannock Falls Gorge
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The Finger Lakes have bolstered their wellness and culinary offerings in recent years, carving out a name for themselves in the luxury travel realm. Inns of Aurora, comprising five historic mansions, debuted a holistic wellness facility in 2021 — set on 350 acres overlooking Cayuga Lake, complete with hydrotherapy pools, meditation areas, and a farm fresh cafe. Forty miles west of Cayuga, The Lakehouse on Canandaigua — situated on, yes, Canandaigua Lake — recently unveiled the Willowbrook Spa, which boasts lakeside barrel sauna sessions among other innovative treatments. Sandwiched between Cayuga and Canandaigua lakes is Seneca Lake, home to the largest of the Finger Lakes wine trails (this might be riesling country, but don't knock the lighter-bodied reds till you try 'em) and foodie draws like the 14-seat F.L.X. Table. Travelers visiting in the coming year will also see the Finger Lakes festival roster return in full force, including Rochester's Lilac Festival in May and International Jazz Festival in July, as well as attractions for the historically inclined road tripper, like Cayuga County's celebration of Harriet Tubman's birth through a number of walking tours and activations rolled out through 2022. — Maya Kachroo-Levine

17. Franklin, Tennessee

Historic downtown Franklin, Tennessee is located just south of Nashville.
Michael Warren/Getty Images

Despite its count of more than 80,000 year-round residents, the very walkable Franklin firmly grasps onto its small-town charms, starting with a quintessentially quaint downtown chock-full of shops and restaurants finding shelter in brick storefronts lining the sidewalks. The uninitiated might know this place for its past — Civil War museums, battleground sites, and historical markers telling the stories of a slave market, race riots, and Black soldiers in the U.S. Colored Troop division of the army all offer points of education and reflection. But the southern city has many modern-day draws as well — for starters, an exciting food and drink scene that includes the Tennessee Whiskey Trail and Arrington Vineyards, the largest winery in the region. Musical events and venues abound, too: The Pilgrimage Music Festival is one of the biggest in the state, and the 7,500-seat FirstBank Amphitheater, newly opened inside a former rock quarry, has welcomed the likes of the Jonas Brothers and Santana to its stage. There's also Leiper's Fork, a quirky-cool enclave filled with antique shops and art galleries. Even more brand-new to the scene is Southall, a 325-acre farm and inn with 62 rooms and suites and 16 cottages opening this June. The lush setting amid rolling hills makes active adventures (hiking, biking, kayaking), wellness pursuits (a spa, meditation, yoga, and two outdoor pools), and nourishing food (the restaurant uses ingredients grown, raised, and foraged on the property) easy to find. All of this and more lie just a short, 30-minute drive from bustling Nashville, making it tempting to tack onto a visit to the capital city. — Alisha Prakash

18. Galápagos Islands

Interior bedroom on Quasar Expedition's M/Y Conservation ship
Courtesy of Quasar Expeditions

The world's largest marine biosphere reserve will expand more than 20,000 square miles next year thanks to a recent presidential decree. The conservation measure seeks to combat illegal fishing by offering increased protection to the thousands of species that populate the archipelago's waters as well as a migration corridor stretching up to Costa Rica used by sharks, whales and other sea life. Come January, travelers can cruise this UNESCO-protected region on new nine-day adventures from Hurtigruten Expeditions and outfitter Metropolitan Touring aboard the 90-guest carbon-neutral MS Santa Cruz II. For a more intimate experience, passengers can book Aqua Expeditions' seven-suite 164-foot superyacht, Aqua Mare, when it debuts in May. At the end of the year, eco-enthusiasts can sail to lesser-explored islands to spot giant tortoises, sea lions, flightless cormorants, Galápagos penguins, and marine iguanas on Quasar Expeditions' new sustainable yacht — the 18-passenger M/Y Conservation featuring biodegradable amenities, renewable energy and a carbon-neutral footprint. Those with timid sea legs should check into the locally owned and run Montemar in the highlands of Santa Cruz Island. — Nora Walsh

19. Greater Palm Springs, California

Sunrise light is golden at his hits the palm trees of Palm Springs, California
Mariah Tyler

Greater Palm Springs is kicking its signature self-care into high gear in the coming year. Taking a cue from its sister property, Sensei Lanai, the new Sensei Porcupine Creek is converting a 230-acre private estate into a luxury wellness experience in Rancho Mirage in 2022. In Palm Springs proper, Agua Caliente Cultural Plaza will celebrate Indigenous art and history alongside the new Spa at Séc-he, where visitors will soak in approximately 12,000-year-old hot springs. Nearby, Fleur Noire Hotel just opened its adults-only casitas and bungalows, with a speakeasy Champagne bar to follow. Unexpectedly, the desert has a budding surf scene — the former Wet 'n Wild waterpark is becoming Palm Springs Surf Club, with a state-of-the-art wave pool, spa, restaurant, and bar; DSRT Surf is set to open a 5.5-acre wave lagoon in Palm Desert; and Kelly Slater himself is bringing a green energy–powered wave basin to Coral Mountain, a proposed new wellness resort with a hotel and residences, set to open in La Quinta by 2023 pending city approvals. And for entertainment outside the splash zone, the $250-million Coachella Valley Arena will host hockey, concerts, and more live events by the end of the year. — Nina Ruggiero

20. Greenville, South Carolina

Falls Park On The Reedy, Greenville, South Carolina
John Coletti/Getty Images

Once in the shadow of Charleston and Asheville, Greenville has emerged in recent years as a go-to destination in its own right — and it keeps giving travelers more reasons to visit. In 2022, the city of just over 70,000 people will welcome a luxury boutique hotel, unveil a new public gathering place, and build on its well-earned reputation as a culinary and craft beer hotspot. The long-awaited, 187-room Grand Bohemian hotel is expected to open its doors this spring, complete with a two-story restaurant and bar, art gallery, and spa. The 60-acre Unity Park will feature plenty of greenspace, an observation tower, baseball fields, playgrounds, and walking and biking trails. And recently opened restaurants, including French Laundry alum Drew Erickson's Camp, Urban Wren, Coral, and an outpost of Nashville's famous Prince's Hot Chicken located inside Yee-Haw Brewing will ensure you're well-fed while in town. — Kevin Gray

21. Ilha Caldeira, Mozambique

Banyan Tree Ilha Caldeira Lounge
Courtesy of Banyan Tree Ilha Calderia

While South Africa and Uganda grab headlines for African wildlife, Mozambique has been quietly making strides protecting 17 percent of its land — including beaches, coral reefs, and islands — showcasing its dedication to its natural beauty both on land and underwater. Ever since the country's 16-year civil war ended in 1992, the southeastern African nation has been aiming to build back in the right ways. Case in point: the private island of Ilha Caldeira, less than seven miles off the coast as part of the Primeiras and Segundas Archipelago, located within the marine-protected area with 20 percent of the country's intact living coral. It's here that the eco-luxury Banyan Tree resort chain has developed one of its most ambitious projects yet, a five-star property — accessible by jetty or helicopter — with 40 private pool villas that will be completely solar powered. Add to that a fish market restaurant with a 270-degree ocean view, the brand's trademark Banyan Tree Spa, and world-class diving, all in a too-pristine-to-believe beach setting, and this island escape is sure to draw attention away from its Indian Ocean neighbors when it opens at the end of 2022. — Rachel Chang

22. Jackson Hole, Wyoming

Peak Color in Jackson Hole Wyoming in Autumn
Jeff R Clow/Getty Images

Those wary of traveling internationally in 2022 will find solace in Jackson Hole, a mountain town with endless open space (Wyoming is the least populated state in the U.S.) and plenty to do. In the winter, life revolves around Jackson Hole Mountain Resort, home to some of the nation's best skiing and snowboarding. In the summer, plan your trip around the Jackson Hole Food & Wine Summer Festival (June 23-25) or head to the nearby Grand Teton and Yellowstone National Parks. For easy access to the mountain town, travelers can hop on one of Aero's high-end, seasonal flights and stay at The Cloudveil off the Town Square or the Caldera House at the base of Jackson Hole Mountain Resort. — Evie Carrick

23. Kafue National Park, Zambia

Kafue River, Kafue National Park, Zambia
Michele Westmorland/Getty Images

Straddling three regions of Zambia, Kafue National Park is the largest (and oldest) in the country, measuring 8,648 miles. In the wildlife-rich Busanga plains — located in the secluded northern side of the park — spend the night at newly opened Chisa Busanga Camp in their bird's nest shaped rooms. Enjoy a silent safari, thanks to e-cruisers or an e-bike safari provided by the property. See wildlife from above with a hot air balloon safari from Shumba Camp or Busanga Bush Camp. Other accommodation offerings in the park include riverfront Ila Safari Lodge and Mukambi Safari Lodge. Both properties offer fishing, walking safaris, boat cruises, and have Instagram worthy pools (perfect for a soak and the traditional safari sundowner: a gin and tonic). — Mazuba Kapambwe

24. Kaunas, Lithuania

Sunset at Kaunas, Lithuania during winter with snow covering the landscape
Andrius Gailiunas/EyeEm/Getty Images

Kaunas, Lithuania has a lofty New Year's resolution. After a century of wars, Soviet rule, and, since the 1990s, independence, this UNESCO Creative City of Design is ready to cultivate a new identity — and it's doing so as one of two European Capitals of Culture for 2022 (alongside Novi Sad, Serbia). The festivities commence in January, with thousands of concerts, festivals, exhibitions, and events throughout the year to celebrate Kaunas' history while cementing its path forward. Also this year, Kaunas will welcome the highly anticipated $30 million Science Island, Lithuania's first national science and innovation center designed by UK firm Malcolm Reading Consultants (MRC). By May, the city's former Magnus Hotel will reopen with sparkly new digs and a posh rooftop under the ibis Styles umbrella. This lively city is also a main stop on the recently unveiled 1,330-mile Forest Trail across the Baltics. And, a host of just-announced Ryanair flight routes, including Madrid to Kaunas, will make visiting this capital of culture a breeze. — Stephanie Vermillion

25. Kyushu, Japan

A general view of the water and islands from Hirado Castle on April 24, 2010 in Hirado, Nagasaki, Japan.
MIXA/Getty Images

Kyushu may be less than two hours from Tokyo by plane, but it feels far from Honshū's well-beaten tourist circuit. The southwesternmost Japanese main island is still largely unexplored, providing those willing to venture off the beaten path with a much different Japan than the one they'll find in its cities. As a warm, subtropical island, Kyushu is home to long, golden beaches and some of Japan's best snorkeling and scuba diving. Inland, the country's most active volcano, Mt. Aso, feeds the island's myriad natural hot springs — many of which offer sea views. And while the island has accommodations that include both hot spring resorts and luxury beachfront villas, nothing tops a stay at Hirado Castle, which was recently restored and renovated to welcome visitors overnight. — Evie Carrick

26. Lanai, Hawaii

Hulopoe Beach Park of Lanai Island of Hawaii
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Wellness opportunities and cultural awareness are showcased along with luxury at Lanai's two Four Seasons resorts. At Sensei Lāna'i, A Four Seasons Resort, guests can now choose the Discover Sensei Experience, offering the ability to enjoy the retreat's amenities without joining the more comprehensive programs. New "Optimal Wellbeing" programs focus on improving performance in tennis and golf along with overall wellness. Four Seasons Resort Lanai is adding an observatory as part of "Love Lanai," featuring cultural experiences designed to share the island's rich heritage. The observatory program will center around the history of Pacific voyaging, native traditions, and astronomy. — Patricia Doherty

27. Las Vegas, Nevada

Resorts World Las Vegas, Conrad
Courtesy of Resorts World Las Vegas

Never bet against the house: The pandemic may have put a damper on Las Vegas, but the ever-on-the-move city is back in a big way for 2022. A massive new development on the Strip, Resorts World Las Vegas, opened in June, has three distinct Hilton properties under one enormous roof, not to mention more than 40 restaurants and bars, plus pools (plural), and a handful of $15,000-a-night villas. Virgin Hotels Las Vegas, the Cromwell, and downtown's Circa Resort & Casino are also giving visitors fresh options on where to stay. The city's pro sports teams — also now plural — are drawing in fans. And off-Strip "immersive experiences," like the Omega Mart by Meow Wolf and the Illuminarium, both at Area15, are lending an additional layer of things to do beyond the expected. Not that there's anything wrong with splashing out on dinner and a show after the past two years. Live acts — like Adele's just-announced residency at The Colosseum — are once again hot tickets, as is a table at chic new supper club Delilah, at the Wynn Las Vegas. Some things, thankfully, never change. — Paul Brady

28. Louisville, Kentucky

Jefferson Street and town square in downtown Louisville, Kentucky, on a cloudy day.
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Your cowboy boots were made for walking the streets of Louisville. Nicknamed "The Bourbon City," an official gateway to Kentucky's bourbon trail, the city is expanding its bourbon footprint in 2022. In October, the Urban Bourbon Trail welcomed the first and only African American–owned distillery in the state, Brough Brothers. Meanwhile, its trailmate, Angel's Envy, will wrap its $8.2-million expansion project complete with a new event space and five tasting rooms in the spring. The city is most well known for hosting the annual Kentucky Derby every spring at the historic Churchill Downs racetrack, and the Downs will open the first installment of its multi-year expansion plan, the Homestretch Club, just in time for the 2022 Derby. There, attendees will be able to enjoy the race with an all-new trackside lounge experience. — Hannah Streck

29. Malaysia

Rendering of interior villa space at Alila Dali Bay in Malyasia
Courtesy of Alila Dalit Bay

Malaysia is home to a beautiful medley of cultures (Chinese, Indian, and Malay) and a diverse smattering of terrain: bustling cities with towering buildings, verdant rain forests with incredible wildlife, and idyllic islands with dreamy beaches. But all of this and more has been closed to the world for much of the pandemic. Now that the island of Langkawi is open via a travel bubble, with the rest of the country expected to follow suit in 2022, travelers can once again experience Malaysia's many gifts. Langkawi, a beach lover's paradise, blends unspoiled nature (UNESCO-listed Kilim Karst Geoforest Park) and unparalleled luxury (Four Seasons Resort, Datai Langkawi), while cosmopolitan capital Kuala Lumpur draws visitors with its gleaming Petronas Towers, delicious hawker food stalls, and shopping. Then there's Borneo, complete with wildlife-packed jungles and a rich Indigenous culture, as well as Desaru Coast, a 3,900-acre area that's home to coveted resorts like the One&Only Desaru Coast, a tropical oasis that opened in early September 2020 (the brand's first in Asia). — Alisha Prakash

30. Maldives

Conrad Maldives Rangali Island, family island aerial view on a sunny day
Courtesy of Conrad Maldives Rangali Island

The Maldives' 1,000+ islands sit in the Indian Ocean like a string of turquoise pearls. The tropical nirvana has 166 accommodation options, including the new Joali Being nature retreat, which leads guests on a transformative wellness journey. Alila Kothaifaru Maldives debuts in February with 80 beach and overwater villas on the Raa Atoll. Coming to the same atoll in May, also with 80 luxury villas, is Emerald Faarufushi Resort & Spa on a massive lagoon primed for snorkeling. The ever-innovative Soneva Fushi has a new experience that includes zip-lining to a six-course meal 30 feet about the sand. Along with Soneva Jani, they've debuted Soneva Soul, a new spa complex melding ancient and modern techniques. Other vacation favorites are unveiling new digs like the sleek, contemporary renovation of Naladhu Private Island and the Conrad Maldives Rangali Island, debuting in February. — Katie Lockhart

31. Newport, Rhode Island

Drone aerial view of Newport Phode Island old tradition building with ocean and yatch port with street summer season
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Newport is considered one of the sailing capitals of the world. It is home to the largest fleet of America's Cup 12 Meter yachts, most of which are available for charter. In May, the coastal town is welcoming a Sailing Museum that is sure to solidify that title. Over the past few years, a slew of hotel openings have closed a much-needed gap for luxury accommodations, including Hammett's Hotel, Brenton Hotel, and The Wayfinder Hotel. The Vanderbilt, Auberge Resorts Collection is debuting the property's highly anticipated transformation conceived by Dallas-based design collective Swoon — the lobby, dining room, and shared areas are now complete with guest rooms finishing early next year. Renowned beverage executive Maxwell Britten has joined the team as chief cocktail curator alongside an amazing chef who cooks up a selection of elevated pub-inspired dishes. And don't miss Giusto, at Hammett's Hotel, which serves up excellent Italian with a Rhode Island twist. — Scott Bay

32. Nile Cruise, Egypt

Uniworld Boutique River Cruises's Sphinx Ship to Egypt
Courtesy of Uniworld Boutique River Cruises

There is no trip that will convert you to a life of river cruising quite like a sail down (well, technically, up) the Nile. In fact, the world's first river cruises sailed in Egypt, a country designed around the central waterway, where it makes sense that the Nile would act as your home base. A typical Egyptian river cruise sets sail from Cairo to Luxor and then Aswan, with the occasional stop to visit an island temple along the way — complete with sights like the Pyramids, Valley of Kings and Queens, Nefertari's tomb, and the Temple of Kom Ombo. In 2022, there's more than one new river cruise to choose from, between Uniworld's newly launched S.S. Sphinx and AmaWaterways' Amadahlia, both of which sailed their inaugural voyages in fall 2021. — Maya Kachroo-Levine

33. Panama

Historic buildings at Casco Antiguo, Panama City. Panama, Central America.
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In late 2021, Panama launched a tourism platform along with the coolest tagline in travel: "Live for More." With a booming coffee scene and a renewed focus on its culture, history, and biodiversity, the Central American nation is ready for its moment in the spotlight. It's an attractive place for those looking to get out of resort mode and into a world open for exploration and adventure. Immersive environmental experiences abound here, including trekking through the rainforest on its suspended hanging bridges and walking to the top of the Volcán Barú, an active volcano with both Pacific and Atlantic Ocean views from the top. There is also abundant opportunity to learn from Panama's seven Indigenous communities, each of whom offer their own personalized experiences and are happy to share their craftsmanship and traditions. Panama offers plenty of luxury, too. In its capital city, check into the American Trade Hotel, centrally located in Panama's Casco Viejo district, a historic neighborhood which happens to also be a UNESCO World Heritage Site. — Stacey Leasca

34. Phuket, Thailand

Old buildings in Cino Portugueses style in Old Town, Phuket, Thailand.
Ratnakorn Piyasirisorost/Getty Images

Before the pandemic, Phuket was beautiful but crowded, full of beach bars and tourists chasing all-nighters. It's still full of energy and surrounded by the same pristine sea glass–colored water, but its luxurious side is finally getting the attention it deserves, from its high-end coffee shops to its cocktail bars. Hide from the world in paradise with a stay in one of the private pool residences at Trisara, featuring kitchens, a private chef, butler service, and breathtaking views over the sea, as well as access to the resort's PRU restaurant, which has earned both a Michelin star and a Michelin green star. Or book a stay at the brand-new V Villas Phuket, which offers a curated selection of 19 private-pool, 1-, 3-, and 4-bedroom villas. Later, party the night away in Phuket Old Town with inventive cocktails at Club No. 43 (think: rum with grilled pineapple juice and espuma), or settle in for a great dinner and a night of daring performances at the Junkyard Theatre, which just launched a weekly Saturday night show. — Alison Fox

35. Pico, Portugal

Road to Mount Pico, Azores
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The islands of the Azores — a Portuguese archipelago in the middle of the Atlantic Ocean some 900 miles west of Lisbon — are more popular than ever, and for 2022, travelers will want to fix their eyes firmly on the second-largest isle: Pico, an alluring, otherworldly locale covered with black, volcanic rocks. Conquering Portugal's highest peak, the cloud-shrouded, 7,713-foot-high Mount Pico, used to be the island's main draw, but a recent uptick in hospitality infrastructure has allowed for more opportunity to partake of Pico's most important agricultural output: wine. Renowned Portuguese winemaker Antonio Maçanita just opened a new winery that comes with bookable design-forward apartments adjacent to the island's unique vineyards. On Pico, grapes are planted on volcanic terroir that are then protected from Atlantic winds with rock walls. Maçanita's ​​Azores Wine Company's mineral, sometimes slightly salty wines could be the perfect celebratory drink after a grueling hike.The crashing waves around Pico are beginning to seduce surfers, too. And there are also ample opportunities to watch for marine life thanks to 20 species of dolphins and whales (including humpbacks and orcas) that can be spotted in these waters. But if you'd rather eat what's in the water: Try lapas, a local shellfish delicacy best served grilled with butter and garlic and finished with a squeeze of lemon. Thankfully, getting to experience all of this has never been easier: Starting July 1, United Airlines will for the first time connect Newark to the island of São Miguel (the Azores' largest island), and from there, it's a quick hop over to Pico. Or you could always get there via direct flights from Lisbon or Porto with Tap Air Portugal's stopover program. — Chadner Navarro

36. Quebec, Canada

Panoramic aerial view of Quebec city and Frontenac Castle (Fairmont Le Chateau Frontenac), Canada
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After over a year of tight pandemic restrictions, Canada reopened to American tourists in 2021, so now might finally be time to plan that trip to the Great White North, starting with the province of Quebec. From the charming, French-influenced cities of Montreal and Quebec City to the region's snow-capped mountains, there's something new to explore every season. In December 2021, the first Club Med mountain resort in Canada, Club Med Quebec Charlevoix, opened, offering all-inclusive ski vacations just a short flight from several major U.S. cities. Regent Seven Seas Cruises is offering a foliage-packed autumn cruise from New York to Montreal in October. No matter what time of year you visit, Le Capitole Hotel in Quebec City and Humaniti Hotel Montreal are top picks for places to stay in the major cities. — Elizabeth Rhodes

37. Queensland, Australia

Burleigh Headland, from Queensland, Australia
Jo Staveley/Getty Images

Australia's highly anticipated international border reopening will be well worth the wait, especially as more travelers seek nuanced cultural experiences and sustainable stays. The northeastern state has long been the gateway for visits to the rightly beloved Great Barrier Reef, and beginning in 2022, visitors can learn about conservation efforts and the ecosystem directly from the area's Traditional Land Owners and Indigenous guides during day trips from Dreamtime Dive & Snorkel. Aboriginal elders and Traditional Land Owners are also working with local operator Gudjuda Tours on a daylong excursion to tag and rescue one of the reef's most beloved creatures: sea turtles. Those who want to take a more extended trip to the Whitsunday Islands can look to Elysian Retreat, recently certified as the area's first fully solar-powered resort, or its carbon-negative sister property Pumpkin Island. Back on the mainland, within the verdant Daintree Rainforest UNESCO World Heritage Site, eco-luxury hideaway Silky Oaks Lodge will finally welcome guests back after its $15-million overhaul. — Sarah Bruning

38. Santa Ynez Valley, California

Autumn Arrives in Santa Barbara Wine Country, also known as Santa Ynez Valley, California
George Rose/Getty Images

Two hours from L.A., the Santa Ynez Valley is rural, unassuming, and coming into its own. The region has grown grapes for decades and has even made a Hollywood cameo in the movie Sideways. The arrival of newer tasting rooms, restaurants, and hotels in recent years has firmly put the area on oenophiles' and travelers' radars. Start with a private olive oil tasting at Global Gardens and hard cider at Tin City Cider in Los Olivos. Follow with pizza pies at Full of Life Flatbread and vino at nearby female-owned A Tribute to Grace and Casa Dumetz. Detour to Firestone Walker's outpost in Buellton for a few limited edition craft brews and finish with dishes such as roasted tomato and fennel risotto at the Ballard Inn's Gathering Table. Though it's technically just beyond the boundaries of the valley in Lompoc, The Hilt Estate, is too good to miss. And once it opens this year as an Auberge property, The Inn at Mattei's Tavern will make for the perfect base from which to explore it all. — Tanvi Chheda

39. São Paulo, Brazil

View of people in their leisure time on Sundays strolling through the new Anhangabau Valley in downtown Sao Paulo
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Known for its dynamic combination of luxury, design, and fashion influence, São Paulo is an international metropolitan hub of arts and culture. It's the largest city in South America, hosting an array of entertainment opportunities such as fabulous hotels, decadent restaurants, high-class museums, and iconic mid-century architecture. With airlines including American adding flights throughout Brazil in 2022 and a flourishing hospitality renaissance throughout the city, São Paulo is well prepared for its anticipated influx of new travelers. A must-visit destination for 2022 is the Rosewood São Paulo, located in the heart of São Paulo's Cidade Matarazzo and housed in a historic landmark building. Here, visitors will encounter 200-plus luxurious guest rooms, suites, and residences, plus six restaurants and bars and two pools. — Molly O'Brien

40. Savannah, Georgia

A historic street in Savannah, Georgia
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This coastal Georgia city is rightly famous for its atmospheric, moss-draped streets and squares, not to mention its hundreds of years of history. But lately Savannah has been boosted by creativity and innovation outside the sometimes frozen-in-amber Old Town, which means now is a particularly compelling time to visit. Make home base the brand-new Thompson Savannah, a slick 13-story tower with interiors by Studio 11 Design that anchors the still-developing Eastern Wharf neighborhood. Phase one of the 54-acre development, which aims to turn a once-industrial waterfront into a contemporary mixed-use destination, includes hundreds of apartments, fitness trails, access to the Savannah River, and multiple bars and restaurants, including Fleeting, a seasonally driven spot inside the Thompson. At the same time, Savannah's other major waterfront destination has also come into its own. The Plant Riverside District, a stone's throw from Old Town, marked its official grand opening in November 2021, putting a bow on a bustling JW Marriott hotel, countless restaurants and bars, and multiple live performance venues all along a rebuilt waterfront. Not that all the action is along the river: The ever-evolving Starland District, a short drive from Johnson Square, has its share of hangouts including Starland Yard, a food truck park that's also home to the excellent Pizzeria Vittoria Napoletana; Two Tides Brewing Company, which pours hazy ales and delicious sours in a super-cool taproom; and Troupial, a Venezuelan cafe. You'll also want to pack Wildsam Savannah, a newly released field guide that helps visitors understand the layers of history (and the contemporary politics) that are fueling the latest renaissance in Savannah. — Paul Brady

41. Seattle, Washington

Montlake, Seattle with Downtown Skyline - Aerial
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Few places offer both an urban and a natural escape in one destination — and the Emerald City might be one of the best. The city center is world-class with top hotel accommodations (Four Seasons Hotel Seattle and Thompson Seattle), locally focused fine dining, and countless cultural sites. Then, just minutes away from all of that is some of the most stunning outdoor recreation out there. Adding to the city's luster is the newly opened Lotte Hotel Seattle. The 189-room tower is bringing high design and refined service to the area. Charlotte, the hotel's restaurant on the 18th floor, serves up an inventive menu that is sure to become an all-time favorite dining experience. The landmark Fairmont Olympic Hotel recently completed a $25-million historic restoration of its public spaces, quickly becoming one of the most Instagrammable spots in town. Plus, its buzzy new culinary showpiece will debut in the months to come. Before leaving Seattle, don't miss a meal at celebrated pasta specialist Brian Clevenger's new restaurant, Autumn. — Scott Bay

42. Sedona, Arizona

A hot air balloon over red rock formations in Sedona, Arizona

Makito Umekita/Travel + Leisure

With tourism already surging thanks to the Instagram fame of attractions like Devil's Bridge, Sedona garnered even more of a following during the pandemic among cooped-up city dwellers enthralled by the destination's red rocks and energy vortexes. In 2022, set your sights on North America's first landscape hotel, Ambiente, home to 40 standalone accommodations (called "atriums"), most with private rooftop decks perfect for stargazing. Opening in May, the sustainability-focused retreat will offer on-site trailhead access — further immersing guests in the Sedona landscape while combating traffic along the city's main highway — and reactivate an ancient waterway to populate a stream running throughout the hotel. Experience Sedona's culinary clout right on property at Ambiente's restaurant, Forty1, housed in a refurbished airstream, or venture next door to Mariposa, the city's must-visit restaurant by chef Lisa Dahl, who pioneered fine dining in this town. — Maya Kachroo-Levine

43. Singapore

A view of Pagoda Street in Singapore's Chinatown district with old shop houses and market stalls selling clothing and souvenirs and several pedestrians walking in the street.
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Singapore reopened to vaccinated American travelers in October 2021 with the introduction of the country's Vaccinated Travel Lane. Travelers can fly from the U.S. on Singapore Airlines' vaccine-mandatory flights; the World's Best airline 26 years running launched Vaccinated Travel Lane flights this fall, and United Airlines plans to follow suit by January 2022. Even in the early stages of reopening to foreign travelers, the city-state is already unveiling new culinary ventures. Recently, chef Julien Royer, behind three-Michelin-star Odette, opened Claudine, and Raffles Singapore unveiled Osteria BBR by Alain Ducasse, while Marina Bay Sands plans to debut chef Tetsuya Wakuda's second restaurant within the hotel in the new year. Of course, there's just as much flavor to be found at Singapore's famed hawker centers, now on the UNESCO list of intangible cultural heritage. As tourists return to Singapore, new cultural attractions follow — from the return of Singapore Art Week, beginning Jan. 14, to the recent unveiling of SkyHelix Sentosa, an open-air ride towering 300 feet above sea level, for anyone still in need of thrills after a 17-hour flight over the Pacific. — Maya Kachroo-Levine

44. Southwest Michigan

In New Buffalo, Michigan, People wait to enter a restaurant

Beaches with ocean-like views were once the main draw to Michigan's southwest coast, but new high-style accommodations and hyper-local experiences are giving us more reasons to go. Where to stay with so many options? Consider the cool new motel-turned-boutique Lake Shore Resort in Saugatuck; The Fields glamping retreat with new spa tents in South Haven; the revamped, modern Harbor Grand Hotel in New Buffalo; or anywhere along the coast with high-touch Bluefish Vacation Rentals, which has killer lakefront homes now stocked with handmade local goods. Hop on the new pedestrian/bike trail in Union Pier, and definitely shop two new woman-owned standouts: the beautifully curated Haven and Ariane Prewitt's AP Cottage, scheduled to open this spring. Women are showing off the culinary scene, too, with everything from a special saison ale — winner of the 2021 Great American Beer Festival — at woman-owned Waypost Brewing Co., to new herb-inspired cocktails at James Beard-winning chef Melissa Corey's Penny Royal Café & Provisions, to James Beard nominee Abra Beherns' Granor Farm, where dinners return this year in a new glass-enclosed barn. — Nina Kokotas Hahn

45. St. Moritz, Switzerland

View of St. Moritz, the famouse resort region for winter sport, from the high hill with the first new snow
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If you're on the hunt for glitz, glamour, and powder for days, look no further than St. Moritz, Switzerland. The Alpine ski town has long been considered the birthplace of winter vacationing. Tourists first flocked to the mountain town in 1864, when hotelier Johannes Badrutt took a few British travelers to the community, promising them bluebird days all winter. It wasn't long until others learned about this hidden winter oasis. Skiers and winter sports enthusiasts flocked to the mountain, which has now hosted the Winter Olympic Games not once, but twice. It's an ideal place for ski bunnies too, thanks to its luxury shopping, and its numerous Michelin-starred restaurants. This winter, head to St. Moritz for its fantastic events like White Surf (Feb. 6, 13, and 20, 2022), an international horse race that takes place across the frozen Lake St. Moritz, and the Snow Polo World Cup (Jan. 28-30, 2022), which happens to be the world's only high-goal tournament on snow. Book a stay at the Badrutt's Palace Hotel, which officially reopened on Dec. 3 for the 2021/2022 season and offers guests the chance to try their hand at high-octane winter sports like skijöring, snowkiting, tobogganing, and even private helicopter tours to the peaks of Piz Bernina and Piz Palü. — Stacey Leasca

46. St. Pete/Clearwater, Florida

Clearwater Beach, Florida Coastline at Night
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The beaches of St. Petersburg and nearby Clearwater are consistently ranked among the best in the U.S. and even the world, but there's more to this destination than white sand, pristine waters, and 361 days of sunshine per year. St. Pete/Clearwater offers more than 30 museums and galleries featuring world-renowned artists like Andy Warhol and Pablo Picasso, as well as the largest collection of Salvador Dalí's work outside of Spain. One could say brewing the perfect beer is also an artform that St. Pete/Clearwater has mastered, with its trail of 35+ locally owned craft breweries. Playfully nicknamed the "Gulp Coast," complete your experience with a digital passport that tracks your beer-sampling progress. These year-round offerings mean you can visit any time, but head over in June 2022 to revel in the 20th anniversary of St. Pete Pride, the largest Pride event in Florida, hosting events for everyone from friends and families to couples and solo travelers. — Jessica Poitevien

47. Todos Santos, Mexico

Waves coming in at Todos Santos, Mexico
Narendran Santhanam/EyeEm/Getty Images

Todos Santos is one of Mexico's pueblo mágicos, or "magic towns," and locals are working to retain its history and culture while embracing the steady stream of travelers who have begun venturing an hour north of Cabo San Lucas to discover its charm. The area saw a handful of new boutique resorts pop up in 2021 that provide luxury amenities while keeping the rugged land and local flora the centerpiece. Wellness-focused Paradero describes itself as a "landscaping project" that just so happens to have luxurious suites, and El Perdido, an all-villa resort less than five miles south, provides all-terrain vehicles so visitors can get to Los Cerritos beach, the local surf break of choice. Oceanfront Rancho Pescadero's multimillion-dollar transformation will be complete in the spring. Bookings for its oceanfront villas and penthouse rooms — some with private rooftops and plunge pools — open in January. Todos Santos has fully embraced farm-to-table dining, with Javier Plascencia's orchard-adjacent Jazamango leading the way, and Santa Terra, a cosmopolitan oyster bar meets arts and entertainment venue concept, is in the process of adding multiple bars and restaurants, plus a glamping site and amphitheater, according to its developer, "without chopping down a single tree." — Nina Ruggiero

48. Udaipur, India

Udaipur city in Rajasthan, India
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After an extremely challenging 20-month closure, India reopened to vaccinated travelers on Nov. 15, 2021. Those looking toward South Asia in the new year, perhaps to see the Taj Mahal in Agra or hit the Goan beaches, should make sure Udaipur is on the itinerary. The city of lakes in southern Rajasthan is thought of as the most romantic Indian destination (even called the "Venice of the East") — but it's not just for honeymooners. From the vibrance of Hathi Pol bazaar and Shilpgram, an artisanal compound on the outskirts of the city with a festival set to return on Jan. 22, to the serenity of Lake Pichola, the artificial lake made in the 14th century, Udaipur is a city where you can fully immerse in Rajasthani culture. A hub of Indian luxury, Udaipur is now home to the country's first Raffles hotel, which opened in October. This private island hotel on Udai Sagar Lake is accessible only by boat — something of a trademark for the over-the-top hotels of Udaipur. Meant to be a flagship hotel in the Raffles portfolio, complete with brand staples (think: bars, both Long and Writers), 101 lavish suites, Rasoi cooking school, and lakeside open-air restaurant Belvedere Point. — Maya Kachroo-Levine

49. Wales, United Kingdom

People walking on a beach in Tenby, Wales which a part of the Coastal Path

Taylor McIntyre/Travel + Leisure

The only path in the world to follow the whole of a country's coastline, the Wales Coastal Path celebrates its 10th anniversary in 2022. Walking its 870 miles would take three months, but its most spectacular stretches can be seen in one visit — and in style. St David's in Pembrokeshire, west Wales, is Britain's smallest city with a mere population of 1,600 and is home to a Medieval cathedral, a luxury hotel inside Roch Castle, some excellent pubs, and the upscale St David's Gin & Kitchen. Hiking paths with unbeatable coastal vistas are within easy reach (try the St David's Head loop) and pass neolithic tombs and hillforts. — Jamie Carter

50. Yucatán, Mexico

San Servasio church in Valladolid, Yucatan, Mexico
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Mérida, the capital of the state of Yucatán, has emerged as one of Mexico's most popular cities thanks to its lively restaurant scene, a busy calendar of cultural events, and a relaxed tropical atmosphere. Increasingly, however, travelers are venturing beyond the city to explore the state's unspoiled nature reserves, ancient Maya sites, and sprawling haciendas — a number now converted into hotels. Among the destinations that are drawing travelers to Yucatán are El Cuyo, a quiet beach town that was long a closely guarded secret of windsurfers. Now visitors can also enjoy gourmet Mexican fare at the El Chile Gordo restaurant and boho-chic lodgings at the new Casa Mate. In Espita, a charming colonial town near Valladolid, is the Casona los Cedros hotel which opened in summer 2021. Sisal, a historic port in the western part of the state, has attracted new interest since being named a Pueblo Mágico at the end of 2020. A new highway completed in April now connects Sisal to Hunucmá (and then beyond to Mérida) making it easier for beachcombers to visit, and perhaps spend the night at the cool Club de Patos. — John Newton

51. Bonus: Space

A view of SpaceX crew capsule approaching International Space Station
Courtesy of SpaceX

This was a monumental year for human spaceflight — not only did NASA and SpaceX achieve a regular cadence of astronaut launches for the first time since the Space Shuttle was retired in 2011, but space tourism has also lifted off in a major way, making space a top destination to visit in 2022. And it's a realistic trip, too, so long as you have the budget for it. Both Blue Origin and Virgin Galactic succeeded in taking passengers to space on short suborbital hops this year, and each company plans to ramp up those flights in 2022 — Virgin Galactic already has more than 600 bookings. The price for a quick jaunt to space? A few hundred thousand dollars. If you have an even bigger budget (say, a couple hundred million dollars), you could charter your own orbital flight in a SpaceX Dragon Capsule, as did entrepreneur Jared Issacman with his Inspiration4 mission in September. There are also tourism trips to the International Space Station in the works; Japanese billionaire Yusaku Maezawa launches on his multi-day journey in December, courtesy of space travel agency Space Adventures and Russia's Roscosmos space agency, which plans to take even more "citizen space explorers" to the orbiting laboratory in the near future. Of course, not everyone has pockets deep enough to cover space travel, but more affordable journeys are on the horizon. Startup Space Perspective plans to launch high-altitude balloon rides to the edge of space in 2024, for the relatively low price of $125,000. Potential dealbreaker, though — the balloons don't actually reach space, maxing out at 100,000 feet in altitude, while space is considered to begin somewhere between 264,000 feet (50 miles) and 327,360 feet ​​(62 miles). But hey, at least there's a bar on board. — Stefanie Waldek

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